Chapter 22, Problem 25RQ

Why is so much effort being poured into genome mapping applications?

What is the purpose and benefit of the polymerase chain reaction?

Describe the precess of Southern blotting

Define and compare the following types of nucleotide substitutions. Which is likely to cause the most dramatic mutant effect? a. missense mutation b. nonsense mutation c. sense mutation

What Art the Features of the Series of -omes? Define the following terms: a. Genome b. Transcriptome c. Proteome d. Metabolome e. Fluxome

How many nucleotides does the human genome contain?

What is the start codon? What are the stop codons? Do any of them code for amino acids?

If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense mutation cause a protein to be shorter, longer, or the same length as the normal 700 amino acid proteins? What would be the effect of a nonsense mutation? A sense mutation?

What are the possible advantages or disadvantages to the organism or its offspring resulting from DNA modification by environmental factors?