Chapter 21.6, Problem 1CYP

Please help me calculate drug dosage from the following information: Patient weight: 35 pounds, so 15.9 kilograms (got this by dividing 35 pounds by 2.2 kilograms) Drug dose: 0.05mg/kg Drug concentration: 2mg/mL

A 25-year-old woman presents to the emergency department with a 2-day history of fever, chills, severe headache, and confusion. She recently returned from a trip to sub-Saharan Africa, where she did not take malaria prophylaxis. On examination, she is febrile (39.8°C/103.6°F) and hypotensive. Laboratory studies reveal hemoglobin of 8.0 g/dL, platelet count of 50,000/μL, and evidence of hemoglobinuria. A peripheral blood smear shows ring forms and banana-shaped gametocytes. Which of the following Plasmodium species is most likely responsible for her severe symptoms? A. Plasmodium vivax B. Plasmodium ovale C. Plasmodium malariae D. Plasmodium falciparum

Standard Concentration (caffeine) mg/L Absorbance Reading 10 0.322 20 0.697 40 1.535 60 2.520 80 3.100

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a. On this first grid, assume that the DNA and RNA templates are read left to right. DNA DNA mRNA codon tRNA anticodon polypeptide _strand strand C с A T G A U G C A TRP b. Now do this AGAIN assuming that the DNA and RNA templates are read right to left. DNA DNA strand strand C mRNA codon tRNA anticodon polypeptide 0 A T G A U G с A TRP

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