Concept explainers
Medical Moment
The Making of the Flu Vaccine: An Example of a Live Growth Medium
Have you ever wondered why health care workers ask about allergic reactions to eggs prior to immunizing patients? Live attenuated vaccines are sometimes created by culturing a virus, such as the influenza virus, in live animals, often chick embryos. The virus is inoculated into fertilized eggs, which are then incubated to encourage the replication of large numbers of virus particles. The contents of the eggs are then collected and purified to create the vaccine.
Today, influenza vaccine preparations contain such low levels of egg protein trial they can be safely administered even in most individuals with allergies though it is recommended that they be medically monitored after receiving the dose. Vaccines in which the virus has been grown in cell culture, rather than in chicken eggs, are also available.
Q. Based on the information here, do you think that influenza viruses can infect (adult) birds? Why or why not?
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Microbiology Fundamentals: A Clinical Approach
- The Adaptive Immune Response Is a Specific Defense Against Infection Researchers have been having a difficult time developing a vaccine against a certain pathogenic virus as a result of the lack of a weakened strain. They turn to you because of your wide knowledge of recombinant DNA technology and the immune system. How could you vaccinate someone against the virus, using a cloned gene from the virus that encodes a cell-surface protein?arrow_forwardDevelopment of Resistance to antimicrobial drugs: What is the difference between a natural, semisynthetic, and synthetic antibiotic? How was the first natural antibiotic discovered? (To answer this question, identify the antibiotic, distinguish between the fungus and the antibiotic, explain where the antibiotic came from, and explain how people knew the antibiotic had antibiotic properties.) Give an example of a strain of bacteria (Genus and species) that is now resistant to commonly used antibiotics (identify the specific antibiotic). Describe the physiological mechanism used by individual bacteria to resist the antibiotic listed in part “3” of this Thought Question. For example, the mechanism could be modification of drug, modification of target, prevention of drug penetration, overproduction of target, or target mimicry. (This means that you must choose a strain of bacteria that we know the characteristic of the bacteria that allows the bacteria to be resistant.) How do…arrow_forwardPhage DNA Virion DNA Attachment |(adsorption) Degraded bacteria DNA Cell (host) Capsid protein Penetration |(injection) Finish drawing the assembly step Synthesis of nucleic acid and protein Assembly and packaging Draw the virions that would infect a new bacteria. Release (lysis) What kind of genetic material will each newly infected cell get? Virus DNA or Bacteria DNA? Virionsarrow_forward
- Why may some bacteria use extracellular enzymes to form blood clots? View Available Hint(s) for Part H The blood clots are a necessary food source for the bacteria. Blood clot can hide bacteria from the immune system. A blood clot leads to tissue necrosis or death, a necessary condition for infection. The blood clots cause disease, which is the intended purpose of the bacteria.arrow_forwardGain of Function research, defined as: "medical research that genetically alters an organism in a way that may enhance the biological functions of gene products." The worry is that this type of research will lead to the release of dangerous viruses and is unethical; others believe it is necessary to treat future pandemic is Gain of Function research unethical? Why?arrow_forwardWisdom tooth, appendix and little to are vestigial structures. What could have been their function in the past? Many types of disease causing bacteria are seen to be mutating lately. What do you think is it's implication to the industry of antibiotic production?arrow_forward
- Virology: What is the difference between sequential and concerted assembly? Herpes viruses sequential assembly and influenza virus concerted .Describe the assembly steps for each virus including important proteins , locations etcarrow_forwardImmunology Question Why is it important to test for both IgG and IgM titers with the IFA test for RMSF? Thank you in advance for answering. It's study for study material.arrow_forwardOuter coating of the bacteria made of polysaccharide in most bacteria, help bacteria to evade phagocytosisarrow_forward
- Virology:To make an mRNA vaccine ,you need 1) a template, 2)an RNA polymerase,3) a mechanism for adding a 5’ cap ( example :capping enzyme or a capping analog).Describe in 1-3 sentences why you need each of these three items to make an mRNA to vaccine .arrow_forwardImmunology studying material. In cases of possible Infectious Mononucleosis, both Heterophile Antibody testing and EBV Antibody testing may be performed. Interpret the following sets of results below as one of the following: No history of EBV suggested Current or Recent EBV suggested Past EBV suggested Format example, Letter A “Current or Recent EBV suggested" A. Positive Heterophile Slide Test only (No EBV testing performed): B. Positive Heterophile Slide Test, Positive EBV VCA IgM & IgG: C. Negative Heterophile Slide Test, Positive EBV VCA IgM & IgG: D. Negative Heterophile Slide Test, negative EBV VCA IgM & IgG & EBNA: E. Negative Heterophile Slide Test, negative EBV VCA IgM, positive IgG, Positive EBNA:arrow_forwardNonearrow_forward
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