Campbell Biology Custom Stony Brook 10 Th Edition
10th Edition
ISBN: 9781269870818
Author: Reece Urry Cain Wasserman Minorsky Jackson
Publisher: PEARSON
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Chapter 19, Problem 19.2CR
Summary Introduction
To determine: The enzymes that are essential for certain types of viruses for the replication but not found in normal cells.
Introduction: Viruses are microscopic organisms that can replicate only inside a host. They cannot remain outside a host cell. The virus uses replication machinery from the host to produce its progeny.
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If a viral host cell has a mutation that interferes with the addition of carbohydrates to proteins (glycoproteins) during processing in the Golgi
apparatus, which of the following processes is most likely to occur?
O A. Viruses released by that host cell would have a decreased ability to infect cells than the virus that originally infected the cell.
B. The virus-encoded protease would be unable to cleave large viral proteins into smaller, functional polypeptides.
OC. The virus would be unable to replicate within the host cell.
D. Viruses released by that cell are novel and would result in infections with higher mortality rates.
You are studying RNA viruses and have discovered one that grows well in a culture of eukaryotic cells. You know that the virus is a single-stranded RNA virus, but you don't know if it is positive or negative stranded. Your lab-mate says, "Well, just treat your cell culture with cyclohexamide and see if the virus replicates its genome." You know that cyclohexamide inhibits protein elongation by binding to eukaryotic ribosomes. What is the basis of your lab-mate's suggestion?
Assume you isolate a single stranded (+) RNA virus. When you examine the proteins in the virus, you find that it does NOT contain replicase enzymes within its capsid. Which of the following is true?
This virus must have a gene that encodes replicase.
This virus will not be able to enter a host cell.
Its genome cannot be translated (the process of translation) by the host cell ribosomes.
A DNA copy of the viral genome has to be made before viral genes are expressed.
This virus must lack surface antigens.
Chapter 19 Solutions
Campbell Biology Custom Stony Brook 10 Th Edition
Ch. 19.1 - Prob. 1CCCh. 19.1 - MAKE CONNECTIONS Bacteriophages were used to...Ch. 19.2 - Compare the effect on the host cell of a lytic...Ch. 19.2 - Prob. 2CCCh. 19.2 - Why is HIV called a retrovirus?Ch. 19.2 - Prob. 4CCCh. 19.3 - Describe two ways in which a preexisting virus can...Ch. 19.3 - Contrast horizontal and vertical transmission of...Ch. 19.3 - WHAT IF? TMV has been isolated from virtually all...Ch. 19 - Are viruses generally considered living or...
Ch. 19 - Prob. 19.2CRCh. 19 - Prob. 19.3CRCh. 19 - Which of the following characteristics,...Ch. 19 - Emerging viruses arise by (A) mutation of existing...Ch. 19 - Prob. 3TYUCh. 19 - Prob. 4TYUCh. 19 - Prob. 5TYUCh. 19 - Prob. 6TYUCh. 19 - EVOLUTION CONNECTION The successof some viruses...Ch. 19 - SCIENTIFIC INQUIRY When bacteria infect an animal,...Ch. 19 - WRITE ABOUT A THEME: ORGANIZATION While viruses...Ch. 19 - Prob. 10TYU
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- List the step common to all viral replication pathways.arrow_forwardDefine prion.arrow_forwardThe second step in viral replication is entry. For bacteriophage, entry usually involves: O a) direct entry of the nucleic acid into the cell. Ob) phagocytosis. c) membrane fusion mechanism of entry. d) receptor-mediated endocytosis.arrow_forward
- The African swine fever virus has two membrane bilayers around the outside of the virus. The outer layer is from the host cell that the virus infects—it takes part of the host membrane with it as it leaves the cell. This membrane then fuses with the next cell the virus infects, and it is known that cholesterol is required in the membrane of the cell being infected in order for the virus to successfully infect the cell. Which of the following is the best explanation for why cholesterol would be required in the membrane of the cell the virus is infecting? Explain your choice in 25 words or less. Viral proteins may not have the correct conformation if the host membrane is less fluid due to lower cholesterol levels The cholesterol forms a channel through the membrane that allows the virus to enter the cell, and without cholesterol the virus cannot enter the cell The cholesterol disrupts a small portion of the hydrophobic core of the membrane to allow the virus to enter the cell, and…arrow_forwardRNA-dependent RNA polymerase performs which of the following functions? O 1) Uncoats the viral genome 2) transcribes retroviral RNA genomes into DNA 3) Replicates RNA into RNA O 4) Replicates DNA into RNA 5) Shuttles RNA genomes into the nucleus for assemblyarrow_forwardDraw a generic (+)RNA virus replication cycle. For viruses, (+) RNA indicates the genomic RNA can be translated directly. How would this differ from the system you drew in #1? Draw a generic (+) RNA virus replication cycle. Indicate which proteins need to be present for RNA replication and translation. Where would they act? Indicate what sequences or modifications would need to be present on the virus RNA for RNA replication and translation. How might a virus differentiate between RNA to be put into progeny virus particles and RNA to be translated into protein?arrow_forward
- What is the function of reverse transcriptase in retroviruses? a) It converts viral RNA into double-stranded DNA Ob) It uses viral RNA as a template for making complementary RNA strands Oc) It translates viral RNA into proteins d) It uses viral DNA as a template for RNA synthesisarrow_forwardReverse transcriptase does not catalyzea) RNA-dependent DNA synthesisb) RNA degradationc) DNA-dependent DNA synthesisd) DNA-dependent RNA synthesisarrow_forwardWhich of the following enzyme is responsible for making a DNA copy from RNA?a) Reverse transcriptaseb) DNA polymerasec) RNA polId) RNA polIIarrow_forward
- You are studying RNA viruses and have discovered a new one that grows well in a culture of eukaryotic cells. You know that the virus is a single-stranded RNA virus, but you don’t know if it is plus or minus stranded. Your lab-mate says, “Well, just treat your cell culture with cyclohexamide and see if the virus replicates its genome.” You know that cyclohexamide inhibits protein elongation by binding to eukaryotic ribosomes. What is the basis of your lab-mate’s suggestion?arrow_forwardThere have been recent outbreaks of dog flu in the US. Why doesn't this virus infect humans? A) The virus can replicate in cells of all species but can only egress from dog cells. B) The genetic code of the virus is the same as that in dog cells but is different from other organisms. C) The virus can only attach to dog cells. D) The virus can enter cells of all species but can only replicate in dog cells.arrow_forwardA cell is produced with a mutation that causes it produce a completely defective TFIIH. What does this likely mean for the fate of the cell? A) The cell's copied DNA may contain more errors. B) the cell cannot make RNA C) Producing RNAs will be slower because the polymerase will fall off the DNA more often. D) The cell cannot replicate its DNAarrow_forward
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What Is A Virus ? ; Author: Peekaboo Kidz;https://www.youtube.com/watch?v=YS7vsBgWszI;License: Standard YouTube License, CC-BY