You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo? a. Knockout b. Knockin c. Conditional knockout d. All of the choices are correct.

Question

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Answer 1

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

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Students have asked these similar questions

A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation? The cell membranes are more resistant than normal. An isotonic solution had been added instead of water. A solution of 0.1 M NaCl had been added instead of water. Not enough water had been added to the red blood cell pellet. The man had sickle-cell anaemia.

With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin

Answer 2

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

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Answer 3

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

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Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

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Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

Answer 8

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer 12

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Answer 13

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.