Fundamentals of Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134396026
Author: Frederic H. Martini, Judi L. Nath, Edwin F. Bartholomew
Publisher: PEARSON
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Textbook Question
Chapter 16, Problem 11CP
Name the two types of cholinergic receptors on the postsynaptic membranes of parasympathetic neurons.
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Match the following statements to the correct neurotransmitter of the autonomic nervous system. Select "Both" if the statement is true of both neurotransmitters.
Secreted by cholinergic fibers.
Receptors for this neurotransmitter may cause either excitatory or inhibitory responses.
Bind(s) to adrenergic receptors.
Receptors for this neurotransmitter are found on all autonomic postganglionic neurons.
This neurotransmitter can increase heart rate.
ANSWER OPTIONS: Acetylcholine or Norepinephrine? Both?
In the parasympathetic branch of the autonomic nervous system, there are two cholinergic synapses
(synapses mediated by acetylcholine) on the way to the target tissue. The first synapse is in the
autonomic ganglion (from the "preganglionic neuron"), and is always mediated by nicotinic
acetylcholine receptors (NACHRS). The second synapse (from the "postganglionic neuron") is on the
target cell, and is mediated by muscarinic acetylcholine receptors (mAChRs).
A. Which of these synapses is expected to always produce a rapid depolarization of the
postsynaptic cell? Explain your answer.
In the parasympathetic branch of the autonomic nervous system, there are two cholinergic synapses
(synapses mediated by acetylcholine) on the way to the target tissue. The first synapse is in the
autonomic ganglion (from the "preganglionic neuron"), and is always mediated by nicotinic
acetylcholine receptors (NACHRS). The second synapse (from the "postganglionic neuron") is on the
target cell, and is mediated by muscarinic acetylcholine receptors (mAChRs).
C. Which synapse is expected to be blocked by removal of Ca2+ from the external solution?
Chapter 16 Solutions
Fundamentals of Anatomy & Physiology (11th Edition)
Ch. 16 - Prob. 1CPCh. 16 - Prob. 2CPCh. 16 - Prob. 3CPCh. 16 - Prob. 4CPCh. 16 - Prob. 5CPCh. 16 - Prob. 6CPCh. 16 - Prob. 7CPCh. 16 - Prob. 8CPCh. 16 - Prob. 9CPCh. 16 - Prob. 10CP
Ch. 16 - Name the two types of cholinergic receptors on the...Ch. 16 - Prob. 12CPCh. 16 - Prob. 13CPCh. 16 - Prob. 14CPCh. 16 - Prob. 15CPCh. 16 - Prob. 16CPCh. 16 - Prob. 17CPCh. 16 - Prob. 18CPCh. 16 - Prob. 19CPCh. 16 - Prob. 20CPCh. 16 - Prob. 21CPCh. 16 - Prob. 22CPCh. 16 - Prob. 23CPCh. 16 - Prob. 24CPCh. 16 - Prob. 25CPCh. 16 - Prob. 26CPCh. 16 - Prob. 27CPCh. 16 - Prob. 28CPCh. 16 - Prob. 1RQCh. 16 - Prob. 2RQCh. 16 - Prob. 3RQCh. 16 - Prob. 4RQCh. 16 - Prob. 5RQCh. 16 - Prob. 6RQCh. 16 - Prob. 7RQCh. 16 - What are the components of a visceral reflex arc?Ch. 16 - Prob. 9RQCh. 16 - Prob. 10RQCh. 16 - Prob. 11RQCh. 16 - All preganglionic autonomic fibers release _____...Ch. 16 - Prob. 13RQCh. 16 - Prob. 14RQCh. 16 - Prob. 15RQCh. 16 - Prob. 16RQCh. 16 - Prob. 17RQCh. 16 - Prob. 18RQCh. 16 - Prob. 19RQCh. 16 - Prob. 20RQCh. 16 - Prob. 21RQCh. 16 - Prob. 22RQCh. 16 - Prob. 23RQCh. 16 - Prob. 24RQCh. 16 - Prob. 25RQCh. 16 - Prob. 26RQCh. 16 - Prob. 27RQCh. 16 - Prob. 28RQCh. 16 - Prob. 29RQCh. 16 - Prob. 30RQCh. 16 - Prob. 31RQCh. 16 - Prob. 1CCCh. 16 - Prob. 2CCCh. 16 - Prob. 3CC
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- In the parasympathetic branch of the autonomic nervous system, there are two cholinergic synapses (synapses mediated by acetylcholine) on the way to the target tissue. The first synapse is in the autonomic ganglion (from the "preganglionic neuron"), and is always mediated by nicotinic acetylcholine receptors (NACHRS). The second synapse (from the "postganglionic neuron") is on the target cell, and is mediated by muscarinic acetylcholine receptors (mAChRs). B. One of these synapses produces a long-lasting hyperpolarization of its target cell. Which synapse, and why?arrow_forwardNervous system functions that directly employ acetylcholine neurotransmitters are referred to as cholinergic. Drugs that might be therapeutic in treating the symptoms of dopamine loss in Parkinson’s disease could include multiple choice 1 dopaminergic agonists and cholinergic antagonists. dopaminergic antagonists and cholinergic antagonists. dopaminergic antagonists and cholinergic agonists. dopaminergic agonists and cholinergic agonists. 2. From the information provided, drugs used to treat Parkinson’s disease symptoms will act at which location? multiple choice 2 The globus pallidus The substantia nigra The striatum 3. Which of the following might be therapeutic in the treatment of Parkinson’s disease symptoms? multiple choice 3 all of these choices listed may be therapeutic increasing dopamine receptor responsiveness monoamine oxidase inhibition increasing dopamine release decreasing dopamine…arrow_forwardBased on the attached figure (Fig. 18.7B in the textbook), what would an increase in activation of D1 receptor-expressing spiny neurons in the striatum cause in downstream basal ganglia structures? Direct and indirect pathways Substantia D1 nigra pars D2 compacta (transient) Frontal cortex Cerebral cortex (transient) + (transient) + (transient) Caudate/putamen VA/VL complex of thalamus (transient) (transient) Globus pallidus, Globus pallidus, external segment internal segment 0 (tonic) (tonic) + (transient) Subthalamic nucleus OA. decreased activity in the globus pallidus external segment (GPe B. decreased activity in the cortex C. increased activity in the subthalamic nucleus (STN) D. decreased activity in the thalamus E. decreased activity in the globus pallidus internal segment (GPI) Parafascicular nucleusarrow_forward
- Identify the targets of the cholinergic and adrenergic neurotransmitters of the ANS.arrow_forwardA)The following structure in the figure is the cell body of a post-ganglionic parasympathetic neurone: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O B) The following structure in the figure is the cell body of a pre-ganglionic sympathetic neurone: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O C) The following structure in the figure is the cell body of a general somatic efferent neurone: A, B, C, D, E, F, G, H, I, J, K, L, M, N, Oarrow_forwarddraw and describe the working of a cholinergic nerve terminal and the receptors upon it, including any feedback mechanism.arrow_forward
- Which of the following describes the disinhibition in the direct pathway of the basal ganglia? Question 6 options: A) Subthalamic nucleus inhibits internal segment of the globus pallidus which disinhibits substantia nigra B) Substantia nigra inhibits striatum which disinhibits the subthalamic nucleus C) Striatum inhibits internal segment of the globus pallidus which disinhibits thalamus D) Striatum inhibits external segment of the globus pallidus which disinhibits thalamusarrow_forwardWhy are the two major neurotransmitters groups known as cholinergic synapses or adrenergic synapses?arrow_forwardName the two major types of cholinergic receptors. Whereare they located?arrow_forward
- Briefly describe where a cholinergic drug acts and how itaffects the postsynaptic receptors. Give two examples ofits possible effects on function.arrow_forwardWhich of the following could be used to describe Norepinephrine (NE)? Select all that apply. hormone neurotransmitter Secreted by most postganglionic parasympathetic fibers uses cholinergic receptors a beta blocker would decrease its activity Secreted by most postganglionic sympathetic fibers Next Droviousarrow_forwardWhat type of synaptic potential (if any; be sure to indicate if any modification is occurring as well) would occur if: a.) An MAO inhibitor type of antidepressant is functioning at an active dopaminergic synapse that increases the rate of sodium flowing into the cell. b.) Prozac is present at an active serotonin synapse where receptor activation increases the flow of potassium out of the cell.arrow_forward
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