Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 13, Problem 20P
A study was performed assessing the association between lifetime analgesic intake and change in estimated glomerular filtration rate (GFR) as measured from two blood samples obtained in 1989 and 2000 among 1645 participants in the Nurses’ Health Study (Curhan, et al. [45]). GFR is a commonly used index of kidney function with lower levels indicating worse kidney function. The following data were presented relating lifetime intake of acetaminophen (the active ingredient in Tylenol) in grams and a decline of ≥ 30% in estimated GFR, which is considered a clinically meaningful decline in kidney function (denoted as a case).
Provide a 95% CI for the OR computed in Problem 13.19.
13.19 What is the estimated odds ratio for being a case comparing Group D to Group A?
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