EBK CONCEPTS OF GENETICS
EBK CONCEPTS OF GENETICS
12th Edition
ISBN: 9780134818979
Author: Killian
Publisher: YUZU
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Chapter 11, Problem 2CS

Although the brother is an immunologically matched donor for his sister, it would be unethical for the clinicians to transplant bone marrow from the brother to the sister. Why?

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uan used the ABO blood testing kit to determine his blood type. His test showed the following                      anti-A                      anti-B                     anti-D                         -                                -                              + + means agglutination was observed - means no agglutination was observed   What is Juan's blood type?     O-     O+     A+     A-
An experiment was performed in mice.  Wild-type bone marrow is used to reconstitute lethally irradiated Cr2-/- mice (wt®Cr2-/-), or vice versa (Cr2-/-®wt). As controls, Cr2-/- bone marrow is used to reconstitute Cr2-/- recipients (Cr2-/-®Cr2-/-), and wild-type bone marrow used to reconstitute wild-type recipients (wt®wt). These mice are then inoculated with the HSV-rd virus at 106 PFU, once at day 0 and then a second time at day 28, and the anti-HSV IgG responses are measured every 7 days, as shown in figure below. a) From the data shown above, on which cell type is the expression of the complement receptor most important for humoral immunity? b) For each of the cell types expressing the complement receptor encoded by Cr2, what is the explanation for their importance in humoral immunity to HSV inoculation?
Can a person be identified by a DNA probe?

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EBK CONCEPTS OF GENETICS

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