Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781260163698
Author: Cowan
Publisher: MCG
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Textbook Question
Chapter 10.3, Problem 20AYP
List five cellular or structural mechanisms that microbes use to resist antimicrobials.
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The type of antimicrobial drug that would be most likely to have toxic effects in
humans based on the premise of selective toxicity when treating microbial infection
would be a drug that
O 1) inhibits the synthesis of the cell wall
O 2) inhibits metabolic pathways
O 3) disrupts the cytoplasmic membrane
4) inhibits protein synthesis
5) All of the above have equal potential to be toxic
Important characteristics of antimicrobial drugs include:
a) readily delivered to the site of infection
b) high toxicity against microbial cells
c) do not cause serious side effects in humans
d) remains active in body tissues and fluids
e) all of the above
Give four main categories of antimicrobial products.
Chapter 10 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 10.1 - State the main goal of antimicrobial treatment.Ch. 10.1 - Identify the sources for the most commonly used...Ch. 10.1 - Describe two methods for testing antimicrobial...Ch. 10.1 - Prob. 4AYPCh. 10.1 - NCLEX PREP 1. An RN is caring for a 26-year-old...Ch. 10.2 - Explain the concept of selective toxicity.Ch. 10.2 - List the five major targets of antimicrobial...Ch. 10.2 - Prob. 7AYPCh. 10.2 - Distinguish between broad-spectrum and...Ch. 10.2 - Prob. 9AYP
Ch. 10.2 - Explain the mode of action of penicillinases and...Ch. 10.2 - Identify two antimicrobials that act by inhibiting...Ch. 10.2 - Prob. 12AYPCh. 10.2 - Identify one example of a fluoroquinolone.Ch. 10.2 - Describe the mode of action of drugs that target...Ch. 10.2 - Prob. 15AYPCh. 10.2 - Prob. 16AYPCh. 10.2 - Explain why antiprotozoal and antihelminthic drugs...Ch. 10.2 - List the three major targets of action of...Ch. 10.2 - Prob. 2NPCh. 10.3 - Discuss two main ways that microbes acquire...Ch. 10.3 - List five cellular or structural mechanisms that...Ch. 10.3 - Prob. 21AYPCh. 10.3 - Prob. 3NPCh. 10.3 - Prob. 1MMCh. 10.4 - Distinguish between drug toxicity and allergic...Ch. 10.4 - Prob. 23AYPCh. 10.4 - Prob. 4NPCh. 10.4 - Prob. 5NPCh. 10 - Microbial resistance to drugs is acquired through...Ch. 10 - Prob. 2QCh. 10 - Prob. 3QCh. 10 - Prob. 4QCh. 10 - Why does the penicillin group of antibiotics have...Ch. 10 - Prob. 6QCh. 10 - Prob. 7QCh. 10 - Conduct research to find out why drugs blocking...Ch. 10 - Prob. 9QCh. 10 - Prob. 10QCh. 10 - You take a sample from a growth-free portion of...Ch. 10 - Prob. 12QCh. 10 - Treating malarial infections is theoretically...Ch. 10 - Can you think of a situation in which it would be...Ch. 10 - Prob. 15QCh. 10 - Prob. 16QCh. 10 - Prob. 17QCh. 10 - Prob. 18QCh. 10 - An antimicrobial drug with a _______ therapeutic...Ch. 10 - Prob. 20QCh. 10 - Prob. 21QCh. 10 - Prob. 1VC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Broad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.arrow_forwarddescribe four modes of action of antimicrobial agents, and give a specific example of how each worksarrow_forwardWhich of the following types of antimicrobial drugs make microbes more susceptible to osmotic pressure? 1) drugs that inhibit nucleic acid synthesis O 2) drugs that inhibit metabolic pathways 3) drugs that inhibit cell wall synthesis 4) drugs that block a pathogen's recognition of its host 5) drugs that inhibit protein synthesisarrow_forward
- List 10 characteristics of an ideal antimicrobial drug.arrow_forwardIdentify two factors( in detail)that make biofilms more tolerant to antimicrobials including their mode of action.arrow_forwardCould an organism that is susceptible to an antimicrobial agent in laboratory testing fail to respond to it when that drug is used to treat the patient? Explain.arrow_forward
- Describe four general mechanisms of antimicrobial resistance.arrow_forwardWhat are the 4 main targets of antimicrobials? Provide the rationale why each is a good target.arrow_forwardWhat are the common neutralizing agents and methods used to inactivate the innate antimicrobial activity of a product?arrow_forward
- Name and describe three mechanisms of acquired antimicrobial resistance tools that microbes may use to thwart drug action.arrow_forwardDescribe four modes of action of antimicrobial agents, and provideexamples of how they work.arrow_forwardIf an infectious agent is sensitive to several antimicrobial drugs, what other considerations might be used to determine the best treatment option?arrow_forward
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