Question 4: Oracle Pharmaceuticals wants to bring covid-19 vaccines for the African Continent. In order to get permission from the government, they have to conduct a trial on human test subjects. They initiated this survey on 2000 healthy male and female university students to know whether they think this vaccine will be effective or ineffective on the human body. The following table presents their test result Effective Ineffective Male Female 618 582 474 326 If one person is selected at random from these 2000 test subjects, find the probability that - 1. The vaccine will be Effective 2. The vaccine will be Ineffective 3. The vaccine will be Effective given that this person is Female. 4. Are the events "Male" and "Effective" mutually exclusive? Why or why not
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- The NIH is funding a trial for a new antidepressant drug. A sample of 1000 people with severe depression are recruited and, at baseline, are given a questionnaire asking about their demographic characteristicsand their mental health. They are then randomly assigned to one of two groups. The treatment group receives the new antidepressant, a pill that must be taken twice a day. The control group receives a placebo pill containing nothing medically active, which must also be taken twice a day. After 10 weeks, researchers locate the individuals and ask them to fill out a questionnaire again assessing their mental health. At the end of the study, researchers find no statistically significant difference in the mental health of the treatment and control groups. Q: Should we be concerned about unbalanced groups here? Is it possible to empirically explore whether this is a problem for this study?Researchers investigate how the presence of cell phones influence the quality of human interaction. Subjects are randomly selected from a population and divided into an experimental group that is asked to leave their phones in the front of the room and a control group that are not asked to leave their cell phones at the front of the room. Subjects are left alone for 10 minutes and then asked to take a survey designed to measure quality of interactions they had with others in the experiment. What statistical test is appropriate?As products come off a large assembly line, they are inspected for quality. They are placed into one of three categories: pass, fail, or need additional inspection. The manager claims that 80% of the products pass the inspection, 5% fail, and 15% need additional inspection. In an effort to increase the passing rate, the machines are recalibrated. After this recalibration, a random sample of 100 products is selected. It is discovered that 85 passed inspection, 2 failed, and 13 needed additional inspection. The manager would like to know if there is convincing evidence that the distribution has changed. What is the value of the chi-square test statistic and P-value? Find the chi-square table here. χ2 = 2.38, P-value is less than 0.0005 χ2 = 2.38, P-value is greater than 0.25 χ2 = 5.10, P-value is less than 0.0005 χ2 = 5.10, P-value is greater than 0.25
- High levels of cholesterol in the blood are associated with higher risk of heart attacks. Will using a drug to lower blood cholesterol reduce heart attacks? The Helsinki Heart Study recruited middle-aged men with high cholesterol but no history of other serious medical problems to investigate this question. The volunteer subjects were assigned at random to one of two treatments: 2051 men took the drug gemfibrozil to reduce their cholesterol levels, and a control group of 2030 men took a placebo. During the next five years, 56 men in the gemfibrozil group and 84 men in the placebo group had heart attacks. Is the apparent benefit of gemfibrozil statistically significant? Using the p-value that you get from your previous z-test statistic, would you conclude that gemfibrozil is probably effective?In randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 125 of 746 subjects in the experimental group (group 1) experienced fever as a side effect. After the second dose, 82 of 627 of the subjects in the control group (group 2) experienced fever as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the a= 0.01 level of significance? Find the test statistic for this hypothesis test. (Round to two decimal places as needed.)High levels of cholesterol in the blood are associated with higher risks of heart attacks. Will using a drug to lower blood cholesterol reduce heart attacks? The Helsinki Heart Study recruited middle-aged men with high cholesterol but no history of other serious medical problems to investigate this question. The volunteer subjects were assigned at random to one of the two treatments: 2051 men took the drug gemfibrozil to reduce their cholesterol levels, and a control group of 2030 men took a placebo. During the next five years, 56 men in the gemfibrozil group and 84 in the placebo group had heart attacks. Is the difference statistically significant at the alpha = 0.01 level?
- High levels of cholesterol in the blood are associated with higher risk of heart attacks. Will using a drug to lower blood cholesterol reduce heart attacks? The Helsinki Heart Study recruited middle-aged men with high cholesterol but no history of other serious medical problems to investigate this question. The volunteer subjects were assigned at random to one of two treatments: 2051 men took the drug gemfibrozil to reduce their cholesterol levels, and a control group of 2030 men took a placebo. During the next five years, 56 men in the gemfibrozil group and 84 men in the placebo group had heart attacks. Is the apparent benefit of gemfibrozil statistically significant? What is the value of the combined proportion (c)? Round to four decimal placesIn a study on the effect of an oral rinse on plaque buildup on teeth, sixteen people whose teeth were thoroughly cleaned and polished were randomly assigned to two groups of eight subjects each. Both groups were assigned to use oral rinses (no brushing) for a 2-week period. Group 1 used a rinse that contained an antiplaque agent. Group 2, the control group, received a similar rinse except that the rinse contained no antiplaque agent. A measure of plaque buildup was recorded at 14 days with means and standard deviations for the two groups shown in the table. Control Group Antiplaque Group Sample Size 8 8. Mean 1.22 0.77 Standard Deviation 0.33 0.33 n USE SALT (a) State the null and alternative hypotheses that should be used to test the effectiveness of the antiplaque oral rinse. O Ho: (H, - H2) = 0 versus H: (, - H2) 0 O Ho: (H1 - H2) = 0 versus H,: (H, - H2) > 0 O Ho: (H1 - H2) = 0 versus H.: (4, - H2) # 0 (b) Do the data provide sufficient evidence to indicate that the oral…The drug Finasteride is marketed as Propecia to help protect against male pattern baldness, and it also may protect against prostate cancer. A large sampleof healthy men over age 55 were randomly assigned to receive either a daily Finasteride pill or a placebo. The study lasted seven years and the men had annual check-ups and a biopsy at the end of the study. Prostate cancer was found in 804 of 4368 men taking Finasteride and in 1145 of the 4692 men taking a placebo. the 95% confidence interval for the risk difference is (-0.077, -0.043). Compared to this confidence interval, a 98% confidence interval for the risk difference is: a.) wider b.) there is not enough information provided to decide c.) half the width d.) the same width e.) narrower
- In the largest clinical trial ever conducted, 401,974 children were randomly assigned to two groups. The treatment group consisted of 201,229 children given the Salk vaccine for polio, and the other 200,745 children were given a placebo. Among those in the treatment group, 33 developed polio, and among those in the placebo group, 115 developed polio. If we want to use the methods for testing a claim about two population proportions to test the claim that the rate of polio is less for children given the Salk vaccine, are the requirements for a hypothesis test satisfied? Explain. A The requirements are not satisfied; the samples are not simple random samples that are independent. B. The requirements are satisfied; the samples are simple random samples that are independent, and for each of the two groups, the number of successes is at least 5 and the number of failures is at least 5. C. The requirements are satisifed; the samples are simple random samples…High levels of cholesterol in the blood are associated with higher risk of heart attacks. Will using a drug to lower blood cholesterol reduce heart attacks? The Helsinki Heart Study recruited middle-aged men with high cholesterol but no history of other serious medical problems to investigate this question. The volunteer subjects were assigned at random to one of two treatments: 2051 men took the drug gemfibrozil to reduce their cholesterol levels, and a control group of 2030 men took a placebo. During the next five years, 56 men in the gemfibrozil group and 84 men in the placebo group had heart attacks. Is the apparent benefit of gemfibrozil statistically significant? Using proportion values rounded to four decimal places, what is the z- test statistic? Round your answer to two decimal places.High levels of cholesterol in the blood are associated with higher risk of heart attacks. Will using a drug to lower blood cholesterol reduce heart attacks? The Helsinki Heart Study recruited middle-aged men with high cholesterol but no history of other serious medical problems to investigate this question. The volunteer subjects were assigned at random to one of two treatments: 2051 men took the drug gemfibrozil to reduce their cholesterol levels, and a control group of 2030 men took a placebo. During the next five years, 56 men in the gemfibrozil group and 84 men in the placebo group had heart attacks. Is the apparent benefit of gemfibrozil statistically significant? State the Null and Alternative Hypotheses. Make sure to define your parameters.