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In the examination of diabetes mellitus patient the elevated ketone bodies level till 300 mg/dl was revealed. Why was this accompanied by considerable increasing ammonia salts excretion till 10 g/day (0,5 g/day in norm)? For the answer: a) list pathways of ammonia dctoxification in different tissues (brain, muscles, and liver), prescnt appropriate reactions; b) specify amino acid which transports ammonia from muscles to kidney, present the reaction of its synthesis, point out enzyme; c) give the scheme of process accelerating in acidosis in the kidney, specify its importance, point out enzyme the synthesis of which is induced under these circumstances; d) write down the formulae of salts in the composition of which ammonia is excreted in ketonemia.

In the examination of diabetes mellitus patient the elevated ketone bodies level till 300 mg/dl was revealed. Why was this accompanied by considerable increasing ammonia salts excretion till 10 g/day (0,5 g/day in norm)? For the answer: a) list pathways of ammonia dctoxification in different tissues (brain, muscles, and liver), prescnt appropriate reactions; b) specify amino acid which transports ammonia from muscles to kidney, present the reaction of its synthesis, point out enzyme; c) give the scheme of process accelerating in acidosis in the kidney, specify its importance, point out enzyme the synthesis of which is induced under these circumstances; d) write down the formulae of salts in the composition of which ammonia is excreted in ketonemia.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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5. In the examination of diabetes mellitus patient the elevated ketone bodies level till 300 mg/dl was revealed. Why was this accompanied by considerable increasing ammonia salts excretion till 10 g/day (0,5 g/day in norm)? For the answer: a) list pathways of ammonia detoxification in different tissues (brain, muscles, and liver), present appropriate reactions; b) specify amino acid which transports ammonia from muscles to kidney, present the reaction of its synthesis, point out enzyme; c) give the scheme of process accelerating in acidosis in the kidncy, specify its importance, point out enzyme the synthesis of which is induced under these circumstances; d) writc down the formulae of salts in the composition of which ammonia is excreted in ketonemia.
Transcribed Image Text:5. In the examination of diabetes mellitus patient the elevated ketone bodies level till 300 mg/dl was revealed. Why was this accompanied by considerable increasing ammonia salts excretion till 10 g/day (0,5 g/day in norm)? For the answer: a) list pathways of ammonia detoxification in different tissues (brain, muscles, and liver), present appropriate reactions; b) specify amino acid which transports ammonia from muscles to kidney, present the reaction of its synthesis, point out enzyme; c) give the scheme of process accelerating in acidosis in the kidncy, specify its importance, point out enzyme the synthesis of which is induced under these circumstances; d) writc down the formulae of salts in the composition of which ammonia is excreted in ketonemia.
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