Antioch was one of the great cities of antiquity which survived and retained some of its significance into the Middle Ages. Why was this city founded and by whom? What kinds of natural advantages did the city enjoy? What vital trade route was associated with Antioch?

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Antioch was one of the great cities of antiquity which survived and retained some of its significance into the Middle Ages. Why was this city founded and by whom? What kinds of natural advantages did the city enjoy? What vital trade route was associated with Antioch?
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