(a) Sketch a graph of the van Deemter equation (plate height versus flow rate). Sketch what the graph would look like if (i) the multiple path term was 0; (ii) the longitudinal diffusion term was 0; and (iii) the finite equilibration time was 0. (b) Shown below are three different van Deemter curves for particles of varying sizes. Propose explanations for their differences based on terms in the van Deemter equation. Thereby explaining why smaller particle size is desirable. HETP (μm) 60 40 20 0 0 2 0 D 5 μm 4 FLOW RATE (mL/min) 6 10 μm Q 3 μm 8

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(a) Sketch a graph of the van Deemter equation (plate height versus flow rate). Sketch
what the graph would look like if (i) the multiple path term was 0; (ii) the
longitudinal diffusion term was 0; and (iii) the finite equilibration time was 0.
(b) Shown below are three different van Deemter curves for particles of varying sizes.
Propose explanations for their differences based on terms in the van Deemter
equation. Thereby explaining why smaller particle size is desirable.
60
8
HETP (μm)
20
0
0
2
0
o
5 μm
4
FLOW RATE (mL/min)
6
10 μm
3 μm
8
Transcribed Image Text:(a) Sketch a graph of the van Deemter equation (plate height versus flow rate). Sketch what the graph would look like if (i) the multiple path term was 0; (ii) the longitudinal diffusion term was 0; and (iii) the finite equilibration time was 0. (b) Shown below are three different van Deemter curves for particles of varying sizes. Propose explanations for their differences based on terms in the van Deemter equation. Thereby explaining why smaller particle size is desirable. 60 8 HETP (μm) 20 0 0 2 0 o 5 μm 4 FLOW RATE (mL/min) 6 10 μm 3 μm 8
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