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A 100 mg iv-bolus of DRUG A is administered to patient and blood samples are collected for 24 hours after dose administration. The AUC(0-12 hours) was 38 (mg-hr)/L. Assume that the clearance (CI) of DRUG Z is 2 L/hr   what percentage of the dose was eliminated in the first 12 hours and what is the approximate half life of this drug?

A 100 mg iv-bolus of DRUG A is administered to patient and blood samples are collected for 24 hours after dose administration. The AUC(0-12 hours) was 38 (mg-hr)/L. Assume that the clearance (CI) of DRUG Z is 2 L/hr   what percentage of the dose was eliminated in the first 12 hours and what is the approximate half life of this drug?

Structural Analysis
Structural Analysis
6th Edition
ISBN:9781337630931
Author:KASSIMALI, Aslam.
Publisher:KASSIMALI, Aslam.
Chapter2: Loads On Structures
Section: Chapter Questions
Problem 1P
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A 100 mg iv-bolus of DRUG A is administered to patient and blood samples are collected for 24 hours after dose administration. The AUC(0-12 hours) was 38 (mg-hr)/L. Assume that the clearance (CI) of DRUG Z is 2 L/hr
 
what percentage of the dose was eliminated in the first 12 hours and what is the approximate half life of this drug?
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