Lab 6

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Health Science

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Dec 6, 2023

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ReMA | Quantitative Foundations | Fall 2023 Lab 6 11/03/2023 1. For each of the studies listed below: i) identify the study design and ii) discuss at least one pro and one con of the study design within the context of the given scenario. If there are alternative study designs that could have been used to answer the research question, you should also: iii) state the alternative study design(s) and iv) state whether you would prefer the given study design or one of the alternative study designs and explain your reasoning. a) Study 1 – You would like to investigate the effectiveness of this year’s flu vaccine. You select a sample of 1,000 individuals who do not have the flu, 450 who received the vaccine and 550 who did not receive the vaccine. You then follow them over time to determine who develops flu symptoms. b) Study 2 – You would like to investigate the effect of childhood home environment (rural/urban) on the risk of developing lung cancer (yes/no) in late adulthood among women in the US aged 65+ who never smoked. You select a sample of 500 individuals who currently have lung cancer and 500 individuals who have never had lung cancer and administer a questionnaire about their home environment during childhood. Assume the prevalence of lung cancer in the source population is known to be ~2.5%. c) Study 3 – You help manage a group of 350 current hospital employees who all began working for the hospital 10 years ago. When individuals were first hired, they were required to complete a basic questionnaire that asked a variety of questions, including questions about demographics and medical history. You would like to investigate the effect of age at the time of initial employment at the hospital (<30/30+) on current job performance evaluation (pass/fail). 1
d) Study 4 (from June 2020) – 2. Use the data from Study 1, provided below, to complete the following questions. Flu No Flu Vaccinated 79 371 Not Vaccinated 368 182 a) Calculate and interpret an appropriate point estimate for a relative measure of the association between vaccination and the onset of flu symptoms. b) Calculate and interpret the 95% confidence interval for the measure you calculated in part a). 2
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