COMP204_S2020_final
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McGill University *
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Course
204
Subject
Computer Science
Date
Jan 9, 2024
Type
Pages
18
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December 2019
Supplemental Examination
Intro to Computer Programming for Life Sciences
COMP-204
March, 2020
EXAMINER:
Mathieu Blanchette
ASSOC. EXAMINER:
Yue Li
STUDENT NAME:
McGILL ID:
INSTRUCTIONS
CLOSED BOOK
X
OPEN BOOK
SINGLE-SIDED
PRINTED ON BOTH SIDES OF THE PAGE
X
MULTIPLE CHOICE
Note: The Examination Security Monitor Program detects pairs of students with unusually similar
answer patterns on multiple-choice exams. Data generated by this program can be used as admissible
evidence, either to initiate or corroborate an investigation or a charge of cheating under Section 16 of
the Code of Student Conduct and Disciplinary Procedures.
ANSWER BOOKLET REQUIRED:
YES
NO
X
EXTRA BOOKLETS PERMITTED:
YES
NO
X
ANSWER ON EXAM:
YES
X
NO
EXAM:
SHOULD THE EXAM BE:
RETURNED
X
KEPT BY STUDENT
PERMITTED
X
Specifications:
Two
double-side pages, 8.5 inches x 11 inches
NOT PERMITTED
CRIB SHEETS:
DICTIONARIES:
TRANSLATION ONLY
REGULAR
X
NONE
CALCULATORS:
NOT PERMITTED
X
PERMITTED (
Non-Programmable
)
ANY SPECIAL
INSTRUCTIONS:
•
Answer all questions on this exam.
•
This exam contains 22 questions on 18 pages.
•
If you need extra space, use the empty pages at the end of the exam.
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page number: 1 / 18
Multiple choice questions (21 points).
Consider the following code
1
c l a s s
A() :
2
def
__init__( s e l f ,
B) :
3
s e l f .C = B
4
5
def
D( s e l f ) :
6
s e l f .C = 1
7
8
def
E() :
9
F = A()
1. (2 points) Which of A, B, C, D, E, or F is a method? Select ALL correct answers.
A
B
C
D
E
F
2. (2 points) Which of A, B, C, D, E, or F is an attribute? Select ALL correct answers.
A
B
C
D
E
F
3. (2 points) Which of A, B, C, D, E, or F is an object? Select ALL correct answers.
A
B
C
D
E
F
4. (3 points) Which line(s) of this program will trigger an error when it is executed. Select ALL correct
answers.
1
d = {
"Mathieu"
:
" Blanchette "
,
"Yue"
:
" Li "
,
15:[1 ,3 ,5 ,15]}
2
d [
"Yue"
]=
" L a n n i s t e r "
3
d [
"Mathieu"
][3]=
"X"
4
d [ 1 5 ]
= 10
5
d [ ( 3 , 8 ) ] += 1
A. Line 1
B. Line 2
C. Line 3
D. Line 4
E. Line 5
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 2
Page number: 2 / 18
5. (3 points) Assume s = "AGAGTC". Which of the following boolean expression(s) will evaluate to
True? Select
ALL
correct choices.
A. s[4] == "T"
B. s[-2:-1][0] == "T"
C. len([ x for x in s if x=="T"]) == 1
D. not ( len(s)==6 or s == set(s) )
E. s[0]<s[1] and s[1]<s[2]
6. (3 points) What would be the sensitivity and specificity of the following prostate cancer prediction
decision tree on the test data given below? Select
ONE
correct answers.
Age
PSA
Gender
Status
76
1.87
Male
Cancer
56
1.74
Female
Normal
59
1.72
Male
Normal
76
1.82
Male
Cancer
75
1.97
Male
Normal
73
1.45
Female
Normal
67
1.63
Male
Cancer
A. Sensitivity = 75%, Specificity = 66.67%
B. Sensitivity = 66.67%, Specificity = 75%
C. Sensitivity = 25%, Specificity = 33.33%
D. Sensitivity = 33.33%, Specificity = 25%
E. Sensitivity = 66.67%, Specificity = 25%
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 3
Page number: 3 / 18
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7. (3 points) The functions below are supposed to determine whether a list of strings contains dupli-
cates (i.e. at least two elements that are equal). Which ones work correctly? Select ALL correct
functions.
1
def
contains_duplicates_A (L) :
2
r e t u r n
le n
(
s e t
(L) )>0
3
4
def
contains_duplicates_B (L) :
5
s = {x
f o r
x
in
L}
6
r e t u r n
le n
( s ) <
l en
(L)
7
8
def
contains_duplicates_C (L) :
9
d = {}
10
f o r
index ,
x
in
enumerate
(L) :
11
d [ index ]
= x
12
i f
l en
(d . keys () )!=
l en
(L) :
13
r e t u r n
True
14
r e t u r n
False
15
16
def
contains_duplicates_D (L) :
17
f o r
index ,
x
in
enumerate
(L) :
18
i f
x
in
L [ index +1:
l en
(L) ] :
19
r e t u r n
True
20
r e t u r n
False
21
22
def
contains_duplicates_E (L) :
23
f o r
index ,
x
in
enumerate
(L) :
24
i f
x
not
in
L [ index +1:
l e n
(L) ] :
25
r e t u r n
False
26
r e t u r n
True
A. contains_duplicates_A
B. contains_duplicates_B
C. contains_duplicates_C
D. contains_duplicates_D
E. contains_duplicates_E
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 4
Page number: 4 / 18
Short answer questions (35 points)
8. (2 points) What will be printed when this program is executed?
1
L = [5 ,
(3 ,6) ,
" Hello "
,
4]
2
output =
[ ]
3
f o r
i
in
range
(2) :
4
x = L . pop (0)
5
y = L . pop (0)
6
output . extend ( [ x ,
x ] )
7
p r i n t
( output )
9. (2 points) What will be printed when this program is executed?
1
def
f u n c t i o n ( x ,
y ) :
2
f o r
i
in
range
( y ) :
3
x += y
4
r e t u r n
x
5
6
x = 2
7
y = 3
8
z =
f u n c t i o n ( x , y )
9
p r i n t
( x , y , z )
10. (2 points) What will be printed when this program is executed?
1
def
f u n c t i o n ( x ,
y ) :
2
f o r
i
in
y :
3
x . extend ( y )
4
r e t u r n
x
5
6
x =
[ 2 ]
7
y =
[ 3 , 4 ]
8
z =
f u n c t i o n ( x , y )
9
p r i n t
( x ,
y ,
z )
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 5
Page number: 5 / 18
11. (3 points) What will be printed when this program is executed?
1
import
math
2
def
fun1 ( x ) :
3
i f
x <0:
4
r a i s e
ValueError
5
r e t u r n
math . s q r t ( x )
6
7
def
fun2 () :
8
fun1 (
-
2)
9
r e t u r n
fun1 (1)
10
11
a = b = c = 0
12
t r y
:
13
a = fun1 (4)
14
b = fun2 ()
15
c = fun1 (9)
16
except
ValueError :
17
p r i n t
(
"Problem"
)
18
p r i n t
(a ,
b ,
c )
12. (3 points) What gets printed when this program is executed?
1
L = [1 ,
6 ,
8 ,
2 ,
8]
2
p r i n t
(
[ x
f o r
x
in
L
i f
x >5]
)
3
p r i n t
(
{x
f o r
x
in
L
i f
x>5}
)
4
p r i n t
(
[ i
f o r
i , x
in
enumerate
(L)
i f
x >5]
)
13. (3 points) Write the function
dot_product
that takes as arguments two lists of integers of the same
lengths, and returns the sum of the products of each corresponding elements.
For example, dot_product([3, 1, 2], [4, 1, 3]) should return 19, because 3*4+1*1+2*3 = 19.
Make
your function as short as possible.
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 6
Page number: 6 / 18
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14. (3 points) What gets printed when this code is executed?
1
def
fun1 ( x ) :
2
p r i n t
( x )
3
4
def
fun2 () :
5
fun1 (3)
6
r e t u r n
1
7
8
fun1 (1)
9
fun2 ()
10
x=fun1 (1)
11
y=fun2 ()
12
p r i n t
( x , y )
15. (3 points) The code shown below executes a binary search over a sorted list. We have added a print
statement on line 6.
What would be printed when binary_search( [1, 1, 3, 4, 6, 7, 8, 8, 9], 3) is executed?
1
def
binary_search ( sequence ,
key ) :
2
low = 0
3
high =
l e n
( sequence )
-
1
4
while
low <= high :
5
mid = ( low + high ) //2
6
p r i n t
( mid )
7
i f
sequence [ mid ] > key :
8
high = mid
-
1
9
e l i f
sequence [ mid ] < key :
10
low = mid + 1
11
e l s e
:
12
r e t u r n
mid
13
r e t u r n
None
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 7
Page number: 7 / 18
16. (6 points) What would be printed when this program is executed? Indicate your answer next to the
arrows on lines 34-49. If executing a particular line would cause an error/exception, just indicate
"ERROR" on that line, but assume that the execution continues.
1
c l a s s
Molecule :
2
def
__init__( s e l f ,
comp) :
3
s e l f . composition = {a : comp . count ( a )
f o r
a
in
s e t
(comp) }
4
5
def
__str__( s e l f ) :
6
r e t u r n
" Molecule
"
+
s t r
( s e l f . composition )
7
8
def
nb_atoms ( s e l f ) :
9
r e t u r n
sum
( s e l f . composition . v a l u e s () )
10
11
c l a s s
Nucleotide ( Molecule ) :
12
def
__init__( s e l f ,
nuc ) :
13
s e l f . name=nuc
14
i f
nuc==
"A"
:
15
Molecule . __init__( s e l f ,
"CCCCCHHHHHNNNNN"
)
16
e l i f
nuc==
"C"
:
17
Molecule . __init__( s e l f ,
"CCCCHHHHHNNNO"
)
18
e l i f
nuc==
"G"
:
19
Molecule . __init__( s e l f ,
"CCCCCHHHHHNNNNNO"
)
20
e l i f
nuc==
"T"
:
21
Molecule . __init__( s e l f ,
"CCCCCHHHHHHNNOO"
)
22
23
def
__str__( s e l f ) :
24
r e t u r n
Molecule . __str__( s e l f )+
"
has
name
"
+
s t r
( s e l f . name)
25
26
def
mystery ( s e l f ) :
27
L=[
"A"
,
"C"
,
"G"
,
"T"
]
28
r e t u r n
Nucleotide (L[3
-
L . index ( s e l f . name) ] )
29
30
31
a = Molecule (
"COO"
)
32
b =
Nucleotide (
"C"
)
33
34
p r i n t
( a )
#
--
>
35
36
37
p r i n t
(b)
#
--
>
38
39
40
p r i n t
( a . nb_atoms () )
#
--
>
41
42
43
p r i n t
(b . nb_atoms () )
#
--
>
44
45
46
p r i n t
( a . mystery () )
#
--
>
47
48
49
p r i n t
(b . mystery () )
#
--
>
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 8
Page number: 8 / 18
17. (4 points) Connect each situation listed on the left to the Python compound type that would be
most appropriate, by drawing a line between each item on the left to an item on the right.
1. The composition of an ecosystem,
de-
scribed as the number of individuals of
each species.
2. The group of symptoms experienced by
each patient at the hospital.
3. The record of the group of animal species
present on the island of Montreal, for each
year from 1900 to today.
4. The spatial coordinates of a tumour in the
brain.
•
List of strings
•
List of set of strings
•
Tuple of float
•
Dictionary with key = strings,
values = int
•
String of lists
•
Dictionary with key = strings,
values = set of strings
18. (4 points) Write a function called
after
that takes a string
S
and a string
marker
as arguments, and
returns a string made of the individual characters that immediately follow every occurrence of string
marker
in
S
. For example, after("AGCAGCCAGCT","GC") should return the String "ACT", whereas
after("AGCAGCCAGCT","GCC") should return the String "A".
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 9
Page number: 9 / 18
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Long answer questions (44 points)
19. (12 points) Write the nutritive_profile function, as described in the comments below. See examples
at the bottom.
1
def
n u t r i t i v e _ p r o f i l e ( meal ,
value_per_gram ) :
2
"""
3
Arguments :
4
meal :
A
d i c t i o n a r y
with
keys =
i n g r e d i e n t s ,
and
5
v a l u e s
=
q u a n t i t i e s
( in
grams )
6
value_per_gram :
A
d i c t i o n a r y
with
keys =
i n g r e d i e n t s
and
7
v a l u e s
=
d i c t i o n a r y
of
elemental
composition .
8
An
elemental
composition
d i c t i o n a r y
9
has
keys = type
of
element
and
10
v a l u e s
=
q u a n t i t y
( in
grams )
per
gram
of
i n g r e d i e n t .
11
Returns :
An
elemental
composition
d i c t i o n a r y ,
with
the
meal ’ s
12
t o t a l
number
of
grams
of
each
type
of
element .
13
"""
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
value_per_gram={
" p i z z a "
:{
" l i p i d s "
: 0 . 5 ,
" carbs "
: 0 . 4 ,
" p r o t e i n s "
: 0 . 1 ,
" s a l t "
: 0 . 1 } ,
40
" milk "
:
{
" l i p i d s "
: 0 . 2 ,
" carbs "
: 0 . 3 ,
" p r o t e i n s "
: 0 . 2 } ,
41
" apple "
:{
" carbs "
: 0 . 2 ,
" p r o t e i n s "
: 0 . 2 } ,
42
" cake "
:
{
" l i p i d s "
: 0 . 3 ,
" carbs "
: 0 . 5 ,
" p r o t e i n s "
: 0 . 1 } ,
43
" p i e "
:
{
" l i p i d s "
: 0 . 2 ,
" carbs "
: 0 . 3 ,
" p r o t e i n s "
: 0 . 2 }
}
44
my_meal = {
" milk "
:1000}
45
p r i n t
( n u t r i t i v e _ p r o f i l e (my_meal ,
value_per_gram ) )
46
# { ’ l i p i d s ’ :
200.0 ,
’ carbs ’ :
300.0 ,
’ p r o t e i n s ’ :
200.0}
47
48
my_other_meal = {
" p i z z a "
:100 ,
" cake "
:100}
49
p r i n t
( n u t r i t i v e _ p r o f i l e ( my_other_meal ,
value_per_gram ) )
50
# { ’ l i p i d s ’ :
80.0 ,
’ carbs ’ :
90.0 ,
’ p r o t e i n s ’ :
20.0 ,
’ s a l t ’ :
10.0}
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 10
Page number: 10 / 18
20. (10 points) You are working at Environment Canada and you are asked to write a program to
calculate the average
monthly
temperature based on past recorded temperatures. You are asked to
write the avg_monthly_temp function, which takes as input
•
A list of temperature measurements (float) for a certain number of
consecutive
days.
•
An object of class MyDate (see below), containing the date of the first measurement in the list.
The function should return a dictionary with keys = month names and values = average temperature
for that month. Only months for which temperatures were recorded should be included as keys in
the dictionary. For example, avg_monthly_temp([20, 24, 22, 18, 16, 16, 18], MyDate(29, "July",
1980) ) should return the dictionary {"July":22.0, "August":17.0}.
Assume the class MyDate is given to you; y
ou do not need to write it.
The class contains an
__init__ method that takes a day (integer), month (string), and year (integer) as arguments. It
also contains a next_date() method, which returns an object of type MyDate that corresponds to
the date of the day following the date on which it is called. For example, if today = MyDate(31,
"December", 2019), then today.next_date() returns object MyDate(1, "January", 2020).
The
next_date method knows about each month duration, as well as leap years, and behaves accordingly.
1
def
avg_monthly_temp ( temp ,
date ) :
2
"""
3
Input :
temp :
a
l i s t
of
temperatures
( f l o a t ) ,
taken
d a i l y ,
4
s t a r t i n g
on
the
s p e c i f i e d
s t a r t
date .
5
date :
Object
of
type
MyDate ,
corresponding
to
6
the
date
of
the
f i r s t
measurement
7
Returns :
D i c t i o n a r y
with
key = month
names
( s t r i n g )
8
and
v a l u e s
= average
temperature
f o r
each
month
9
"""
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 11
Page number: 11 / 18
21. (12 points)
A microscopy image shows a set of cells of different types.
The image has been treated to identify edges in the image
(boundary of cells). It has a black background, and white
edges. Bacteria of type bacillus have a long, narrow shape.
Bacteria of type E. coli have approximately round shape.
Human cells are large and have an approximately round
shapes.
Our goal is to write a program that counts the
number of each type of cells present in the image.
a) (6 points) Start by writing a modified version of the seedfill function seen in class and reproduced
below. Your modified version should return a
tuple
of 3 numbers: number of pixels in the portion
filled, length of the portion filled, height of the portion filled.
For example, on the image shown
below, seedfill(4,3,
.....
)
should return (10, 4, 3), and seedfill(9,12) should return (11,7,3).
You
can either indicate the changes directly on the code below, or rewrite the function (without the
comments) using one of the supplementary pages at the end of this booklet.
1
def
s e e d f i l l (im ,
seed_row ,
seed_col ,
f i l l _ c o l o r , bckg ) :
2
"""
3
Arguments :
4
im :
The
image
on
which
to
perform
the
s e e d f i l l
algorithm
5
seed_row
and
seed_col :
p o s i t i o n
of
the
seed
p i x e l
6
f i l l _ c o l o r :
Color
f o r
the
f i l l
7
bckg :
Color
of
the
background ,
to
be
f i l l e d
8
Returns :
Number
of
p i x e l s
f i l l e d
9
Behavior :
Modifies
image
by
performing
s e e d f i l l
10
"""
11
s i z e =0
12
13
n_row ,
n_col = im . shape
14
15
f r o n t =[( seed_row , seed_col ) ]
16
17
18
while
l e n
( f r o n t ) >0:
19
20
r ,
c =
f r o n t . pop ()
21
22
im [ r ,
c]= f i l l _ c o l o r
23
24
s i z e+=1
25
26
27
f o r
i
in
range
(
max
(0 , r
-
1) ,
min
(n_row , r +2)) :
28
29
f o r
j
in
range
(
max
(0 , c
-
1) ,
min
( n_col , c+2)) :
30
31
i f
im [ i , j ]==bckg
and
( i , j )
not
in
f r o n t :
32
33
f r o n t . add (( i , j ) )
34
35
36
r e t u r n
s i z e
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 12
Page number: 12 / 18
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b) (6 points) Write the function count_cells, which takes as argument a black-and-white image
(with black background and white edges), and returns a
tuple
of three integers: the number of
bacillus cells, E. coli cells, and human cells (in that order).
•
Bacillus cells have between 5 and 12 black pixels (inclusively), and have a ratio of length to
height of at least 2 (i.e. their length must be at least twice their height)
•
E. coli cells have between between 4 and 10 pixels (inclusively), and have a ratio of length to
height of at most 1.5 (i.e. their length must be at most 1.5 times their height)
•
Human cells have size at least 15 pixels, and have a ratio of length to height of at most 1.5.
•
Any region that does not meet the conditions above is not a cell.
For example, called on the image shown on the previous page, the count_cells function should return
the tuple (2, 1, 1), because we have (in clock-wise order, starting from the top left)
•
An E. coli cell of 10 pixels, length 4 and height 3.
•
A Bacillus cell of 11 pixels, length 8, and height 2.
•
A Bacillus cell of 11 pixels, length 7, and height 3.
•
An object that is not a cell, of 3 pixels, length 2, and height 2.
•
A human cell of 28 pixels, length 5, and height 7.
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 13
Page number: 13 / 18
22. (10 points) In this question you will write code to simulate the following system. In a medical clinic,
there are patients and doctors. Patients are in a waiting list, in the order in which they arrived at the
clinic. Each patient has a certain set of symptoms that are present. Each doctor is only accredited
to treat only a certain set of symptoms. If a patient has at least one symptom the doctor is unable to
treat, the doctor will not treat that patient at all. If a doctor is able to treat a patient, the procedure
will take exactly one hour. A doctor can only treat one patient at a time, and each patient only
needs to be treated by one doctor. Assuming we start with a given waiting list of patients, and set
of available doctors with their respective accreditation, the goal of our simulation it to determine
how many hours it will take before all patients are treated.
You have have access to the Patient and Doctor classes defined below.
a) (2 points) Write the can_treat_patient method of the Doctor class, which takes as argument a
Patient object and returns True if the doctor is able to treat the patient, and False otherwise. A
doctor can treat a patient if they can treat
all
of the symptoms that patient has.
1
c l a s s
Patient :
2
def
__init__( s e l f ,
name ,
symptoms ) :
3
s e l f . name = name
4
s e l f . symptoms = symptoms
5
6
c l a s s
Doctor :
7
def
__init__( s e l f ,
name ,
can_treat ) :
8
s e l f . name = name
9
s e l f . can_treat = can_treat
10
s e l f . a v a i l a b l e
= True
11
12
# WRITE THE
can_treat_patient METHOD HERE
Course: COMP-204 Intro to Computer Programming for Life Sciences
Page 14
Page number: 14 / 18
b) (8 points) Write the function time_until_empty, which takes as argument a
List
of Patient
objects, and a
List
of Doctor objects. Each hour, the patients at the front of the waiting list get
assigned to an available doctor who can treat their symptom, if one is available.
If a patient’s
symptoms cannot be treated by any available doctor, the patient remains in the waiting list.
In the example given below, time_to_empty(patients, doctors) should return 3, because:
•
Hour 1: Ana is treated by Dr. House, Suzanne is treated by Dr. Greene, Elvis is treated by Dr.
Yang, and the other patients cannot be treated.
•
Hour 2: Amol is treated by Dr. House, Sharon is treated by Dr. Greene, and the other patient
cannot be treated.
•
Hour 3: Frank is treated by Dr. House.
1
# WRITE THE
time_to_empty
FUNCTION HERE
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
d o c t o r s
=
[ Doctor (
" Green "
,
{
" headache "
,
" dementia "
}) ,
32
Doctor (
"House"
,
{
" sore_throat "
,
" headache "
,
" h e a r t _ f a i l u r e "
,
" dementia "
}) ,
33
Doctor (
" P y c e l l "
,{
" sore_throat "
,
"cough"
,
" headache "
}) ,
34
Doctor (
"Yang"
,
{
" h e a r t _ f a i l u r e "
,
" arrythmia "
,
"cough"
}) ,
35
Doctor (
"McCoy"
,
{
" klingon_fleshwound "
})
]
36
37
p a t i e n t s
=
[ P a t i e n t (
"Ana"
,
{
" h e a r t _ f a i l u r e "
}) ,
38
P a t i e n t (
" Suzanne "
,{
" headache "
,
" dementia "
}) ,
39
P a t i e n t (
"Amol"
,
{
" h e a r t _ f a i l u r e "
,
" sore_throat "
}) ,
40
P a t i e n t (
" Sharon "
,
{
" dementia "
}) ,
41
P a t i e n t (
" E l v i s "
,
{
" h e a r t _ f a i l u r e "
,
" arrythmia "
}) ,
42
P a t i e n t (
" Frank "
,
{
" h e a r t _ f a i l u r e "
,
" headache "
}) ]
43
44
t=time_to_empty ( p a t i e n t s ,
d o c t o r s )
45
p r i n t
( t )
#
should
p r i n t
3
Course: COMP-204 Intro to Computer Programming for Life Sciences
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