Annotated Biblography 301

6. (Chapter 15 - 47b) An aromatic compound, C9H12 has the following H NMR spectrum and a peak at 750 cmt in its IR spectrum. Answer the following questions. Chem. shift Rel. area 1.19 2.31 2.64 7.13 1.50 1.50 1.00 2.00 TMS 10 3 O ppm Chemical shift (6) 4(a). The IR peak at 750 cm in its IR spectrum indicate that the compound is. disubstituted = 4(b) The name of the compound is = Intensity-

Figure 1 shows a 1H NMR spectrum of a solution that was prepared by dissolving 1,3,5-trimethoxybenzene (10.22 mg) in CDCl3 (1.470 g).T What is the concentration in mol dm–3 of CHCl3 present in the CDCl3? (Density of CDCl3 = 1.500 g mL–1.)

please fill out the chart or part of it based on the compound

DEPT-135 DEPT - 90 DEPT - 45 T 200 CDS-03-521 180 4/5 160 140 - H₂CO T 120 75% + 100 ppm U 80 LL 60 40 20 0

Compare the 13C NMR spectra of isoborneol and camphor. Explain which peaks can be used to determine whether the oxidation was successful. Propose a mechanism for this oxidation. To simplify the structures, use benzyl alcohol to draw the mechanism instead of isoborneol. Include the formation of any byproduct(s) in the mechanism.

3. 'H-NMR interpretation When dissolved in CDC13, phenacetin shows 6 signals. All of the peaks are sharp, except for the signal f not below. Draw the chemical structure of phenacetin, labeling each hydrogen with an alphabetical letter. Make a larger version of the chart below (half or full page), and complete it with the missing information. Explanation of splitting patter 8 (ppm) Letter # H (integration Splitting pattern value) 7.94 f 1 Broad singlet 7.36 e 6.80 d 3.98 с 2.09 b 1.38 a Extra Credit Question 4. Describe/predict how the 'H-NMR spectrum differs for acetaminophen.

An oxidation reaction was conducted using cyclohexanol and NaOCl to make cyclohexanone. How can we know that the IR spectra for cyclohexanone is in fact cyclohexanone apart from the title. Analyze and annotate the IR spectra to prove its identity.

Using the attached infrared spectroscopy spectrum for the compound 2-Heptanone, identify the functional group and any observed characteristic absorbtions in cm-1. Compare with the attached roadmap for interpreting IR spectra.

this is the spectral data for 4-cyclohexene-cis-1,2-dicarboxylic acid - What should the integral be for the peak at 12.25 ppm?

4. Propose a structure for an organic compound with structural formula CioH13NO2 based on the given IR and H NMR spectra. Explain your answer by interpreting the spectra 7.4 7.2 7.0 6,8 4.0 3.8 1.4 1.2 TMS Impurity 8. 7 5 4 3 2 &H (ppm) 100 90 80 70 60. 50 40 30 20 10 4000 3600 3200 2800 2400 2000 1800 1600 1400 1200 1000 800 650 Wavenumber (cm-) Transmittance (%)

Please help me identify the peaks for the IR of 4-bromobenzoic acid as seen in the photo!

Maletic anhydride  1,4-dimethoxybenzene  benzil anthracene  benzaldehyde  benzoic acid  3-nitrophthalic acid  salicylic acid  benzophenone

Please explain how to figure out, esp. COSY

Using the attached infrared spectroscopy spectrum for the compound Heptanoic Acid, identify the functional group and any observed characteristic absorbtions in cm-1. Compare with the attached roadmap for interpreting IR spectra.

Using the attached infrared spectroscopy spectrum for the compound Tetrahydrofuran, identify the functional group and any observed characteristic absorbtions in cm-1. Compare with the attached roadmap for interpreting IR spectra.

Briefly answer the following Questions 1. What is the commercial use of ibuprofen? 2. What are the important criteria of a good resolving agent in the resolution of ibuprofen? 3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen?

Attached is the NMR data sheet for 4-cyclohexene-cis-dicarboxylic anhydride. How do I interpret it to complete the table? The structure is supposed to show stereochemistry for diastereotopic protrons and chiral centers.

draw the strucutre based off the IR spectrum, 1H NMR spectrum, and 13C NMR spectrum for Compound B. Compound B may be prepared by treating Compound A with borane/THF complex followed by oxidative work-up.  Compound A (C8H16) → Compound B (C8H18O)

In this IR and NMR - what functional group is being shown?(carboxylic acid, ester, amide, acid anhydride, or acid chloride)

Please fully annotate this IR spectrum in the picture below, no need to annotate the fingerprint region (400-1500 cm-1). Thank you so much!!

Which set of H's in the phenacetin analog shown below correspond to HA/HA' in the 1H NMR spectrum shown below? Phenacetin1HNMR Chem235.12.fid 7.9 7.8 7.7 7.6 HA/HA' HB/HB' N A/A' 7.5 11 Group 1 one H3C 10 B 7.2 7.1 7.0 F1 (ppm) C/C' ZI 6.8 6.7 6.6 6.5 6 f1 (ppm) 5 [Choose ] [Choose ] CH3 Group 2 900 -800 700 -600 -500 400 -300 -200 100 -0 > -3800 3600 3400 3200 -3000 2800 2600 2400 -2200 -2000 1800 -1600 1400 - 1200 -1000 -800 600 -400 -200 -200

Please help annotate this IR spectrum in the picture below, thank you so much!!

A student was trying to determine the identity of an unknown compound.  The melting point of the compound was 117-118oC. The student narrowed the possible compound down to the following:   Compound Melting Point Range acetanilide 113-115oC fluorene 114-116oC mandelic acid 120-122oC A second student, doing the same experiment as above, found that their melting point was 100-108oC.  What is wrong with the student’s melting point? Propose two reasons why the melting point could be incorrect. View keyboard shortcuts

The Lipinski’s rules indicate poor absorption when:   The molecular weight is > 500 Da The number of hydrogen-bond donors is greater than 5. The number of hydrogen-bond acceptors is greater than 10. The partition coefficient [measured as log(P) = log10 {[drug] n-octanol / [drug] water}] is greater than 5.   27.A. Indicate whether or not the molecule shown below (fluconazole) follows the Lipinski’s rules. Analyze each rule one by one, indicating which are the hydrogen-bond donors and hydrogen-bond acceptors and calculate log (P). According to your analysis, will fluconazole have good or bad absorption. MW = 306.271 g/mol  Solubility in water = 1 mg /ml  Solubility in octanol > 60 mg/ml

The partial ¹H NMR spectrum for ester A is as below. 10 (i) (ii) (iii) Hc. H₂ 9 Ha 8 OCH 3 7 6 5 Give the approximate chemical shifts for protons H₂, H₂ and Hc. Explain the difference in chemical shift for Ha and Hc. Name the splitting pattern for Ha.

Using the attached infrared spectroscopy spectrum for the compound Ethyl Pentanoate, identify the functional group and any observed characteristic absorbtions in cm-1. Compare with the attached roadmap for interpreting IR spectra.

Find information on: 1. DDT 2. EDTA 3. orotic acid 4. сarboplatin 2. Propose the approximate shift/splitting pattern/etc. for each type of hydrogen that would be seen in an 'H-NMR spectrum Identify the # of each type of each carbon (i.e. how many peaks in the 13C spectra) 3. Identify infrared (IR) active bonds within each molecule 4.

Having trouble with 21, how would I calculate when there’s two moles of a halogen?

PLEASE ANSWER THIS QUESTION!!!!