designer-genes-project-1702391996

Designer Genes Project Applied Georgia Standards of Excellence SB2. Obtain, evaluate, and communicate information to analyze how genetic information is expressed in cells. b. Construct an argument based on evidence to support the claim that inheritable genetic variations may result from: · new genetic combinations through meiosis (crossing over, nondisjunction) · non-lethal errors occurring during replication (insertions, deletions, substitutions) and/or · heritable mutations caused by environmental factors (radiation, chemicals, and viruses SB3. Obtain, evaluate, and communicate information to analyze how biological traits are passed on to successive generations. a. Use Mendel’s laws (segregation and independent assortment) to ask questions and define problems that explain the role of meiosis in reproductive variability. b. Use mathematical models to predict and explain patterns of inheritance. (Clarification statement: Students should be able to use Punnett squares (monohybrid and dihybrid crosses) and/or rules of probability, to analyze the following inheritance patterns: dominance, codominance, incomplete dominance.) Objective: Genetics follows certain rules, as illustrated by Punnett squares, principles of dominance and recessiveness, and rules related to the location of alleles on the chromosomes. In animals, such as mice, certain traits are expressed in predictable ways. In this project, you are going to design your own imaginary species, create traits for the species that follow genetic rules that you have studied, and create a model of your species. You will be responsible for creating both parents (Mom and Dad) and the offspring of your designer species. Your final project should have the following elements: a. Family of five (2 parents and 3 offspring) of your creation fully described and illustrated (to show the phenotypes), that exhibit at least five (5) traits. Be sure you include a description and sketch of each of the traits that your species will exhibit, listing genotypes (ex. TT) and phenotypes (ex. tall) for each. Your list must include the type of inheritance each trait shows, and the traits must include at least one non-Mendelian trait ( beyond dominant and recessive ). One trait may cause a genetic disease or be fatal when homozygous. (25 points) b. Create five Monohybrid Punnett squares (a cross for each of the five traits inherited from the parents) to show which traits the offspring inherited from the parent creatures. This ensures the offspring have the correct and possible traits based on inheritance. Make sure you use different letters for each trait (ex. T or t for height and B or b for fur

color), and include at least one non-Mendelian trait. ( Monohybrid cross video ) ( Baby Steps through a Punnett Square ) (20 points) c. Create a basic Pedigree showing the passage of only one of the five traits for your family of five. Be sure to label all parts (including generations) and the trait and genotypes. (Pedigree Help Video) ( How to draw a pedigree chart ) (15 points) d. Build one Dihybrid Cross (yes - a 16 square Punnett showing the inheritance of two traits) using two of the traits of your parent species. ( Dihybrid Cross Video ) ( Dihybrid cross shortcuts Video ) (20 points) e. Write a summary of your findings . Discuss the value of genetic counseling, the benefits of variation within species and opportunities for mutations that are heritable. ( CDC Genetic Counseling ) ( Mutations ) (20 points) f. Submit the completed assignment to the Unit 8 Lesson 8 Schoology assignment drop box - you are NOT expected to complete the discussion assignment for the Connexus lesson. See the project submission and scoring details by clicking HERE .

Monohybrid Punnett Squares 20 points Missing or incorrect Punnett squares for all five traits. Incomplete or partially correct Punnett squares for some of the traits. Complete and correct Punnett squares for most of the traits. Complete and correct Punnett squares for all of the traits. Complete and correct Punnett squares for all of the traits, with additional evidence of advanced understanding. Basic Pedigree 15 points No attempt at creating a basic pedigree. Incomplete or inaccurate basic pedigree. Complete and accurate basic pedigree with some missing information. Complete and accurate basic pedigree with all necessary information. Complete and accurate basic pedigree with all necessary information, and includes additional advanced details. Dihybrid Cross 20 points No attempt at creating a dihybrid cross. Incomplete or incorrect dihybrid cross. Complete and correct dihybrid cross, but with minor errors or omissions. Complete and correct dihybrid cross without errors or omissions. Complete and correct dihybrid cross without errors or omissions, and includes additional advanced details. Summary of Findings 20 points No summary provided. Incomplete or unclear summary of findings. Adequate summary of findings with some missing information. Clear and concise summary of findings. Thorough and well-explained summary of findings with additional insights.